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Heterocyclic Building Blocks Halogenated Heterocycles Non-Halogenated Heterocycles Aromatic Heterocycles Aliphatic Heterocycles Heterocyclic Building Block Thiadiazoles Thiophenes Thiazolidines Thiazoles Thiazines Tetrazoles Quinuclidines Isoquinolines Isoxazoles Isothiazoles Oxetanes Thiomorpholines Benzodioxans Benzofurans Benzimidazoles Benzoxazoles Benzothiophenes Naphthyridines Spiroes More >>
Organic Building Blocks Organic Building Blocks Fluorinated Building Blocks Aryls Aliphatic Hydrocarbons Trifluoromethyls Difluoromethyls Sulfoxides Azoes Thioesters Isocyanates and Isothiocyanates Isocyanides Nitriles Alkyls Sulfones Nitroes Nitrates and Nitrites Thioureas Thiols Sulfides Iodides Sulfamides Sulfonates Hydroxylamines Carboxylic Acid Salts More >>
Catalysis Chemistry C-H Activation Diketone Ligands Non-Precious Metal Catalysts Nitrogen-Donor Ligands Carbon-Donor Ligands Photocatalysts Cross-Coupling using Transition Metal Catalysts Transition Elements Phosphorous Compounds Cross-Coupling Other Ligands Hydrogenation Olefin Metathesis Olefin Ligands Rare-Earth Elements Organocatalysts Main-Group Elements Metal Catalysts
Asymmetric Synthesis Chiral Resolution Reagents Chiral Catalysts, Chiral Ligands and Chiral Reagents Chiral Building Blocks Chiral Auxiliaries
Organometallic Reagents Grignard Reagents Organolithium Organoboron Organogermanium Organomercury Organotin Organobismuth Organosilicon Organoarsenic Organometallic Reagent
Synthetic Reagents Acids & Bases C-C Bond Formation C-X Bond Formation (Halogen) C-X Bond Formation (Non-Halogen) Chelation and Complexation Compounds Coupling Dehydrating Reagents Hypervalent Iodine Compounds Inorganic Salts Polymer-Supported Reagents Radical Chemsitry Protection, Deprotection and Derivatization Phase Transfer Catalysts Wittig Reagents Fluorination Reagents Synthetic Reagent Others Reduction Halogenation Reagents Condensation Agents Oxidizing Agents
Specialty Synthesis Ionic Liquids Enzyme-Mediated Synthesis Solid Supported Synthesis Fluorous Synthesis
Stains and Dyes Direct Dyes Basic Dyes Mordant Dyes Sulfur Dyes Azoic Dyes Pigments Vat Dyes Oil Dyes Disperse Dyes Dye Intermediates Other Stains and Dyes Acid Dyes
Chemical Biology PEGylation Photolabile Protecting Group Conjugation Chemistry Nucleic Acid Chemistry Linkers and Crosslinkers Peptide Chemistry Glycoscience

Pharmaceutical Intermediates

Dental & Oral Agents Honokiol
Antifungals Eberconazole Caspofungin Sertaconazole Isavuconazonium Sulfate G1 MK 3118 Anidulafungin Tavaborole Voriconazole Micafungin Efinaconazole Posaconazole VT-1161 Luliconazole
Immunological Agents FK-3311 Solupred Tofacitinib AJM-300 Ozanimod Mycophenolate Mofetil APD-334 Darbufelone Icatibant Ridogrel Mycophenolate Sodium Decernotinib Leniolisib Apremilast Iguratimod Baricitinib KRP-203
Antineoplastics Quizartinib Belinostat Imatinib Sonidegib Apalutamide Imiquimod Sorafenib Rebimastat Lapatinib Venetoclax Glufosfamide Rimiducid Acelarin Osimertinib Midostaurin PF 04929113 Arzoxifene NSC 350625 MK-2206 Alpelisib Telatinib Pacritinib Firtecan pegol Rigosertib More >>
Antivirals BMS-955176 Vedroprevir Ombitasvir Boceprevir Valacyclovir Paritaprevir Abacavir FV-100 Raltegravir Atevirdine Efavirenz Cabotegravir Taribavirin hydrochloride Clevudine V-116517 Brincidofovir Saquinavir Lamivudine Emtricitabine Tenofovir Disoproxil Deleobuvir Dasabuvir Doravirine Simeprevir More >>
Respiratory Tract Trantinterol Broxaterol Sinapultide Pirfenidone Fudosteine Riociguat Methylprednisolone OC000459 TD-4208 Bedaquiline Olodaterol Aclidinium Bromide Masilukast VX-661 Vilanterol Zileuton Treprostinil Fluticasone Furoate Selexipag Sitaxentan Ambrisentan Roflumilast Sivelestat Macitentan More >>
Cardiovascular Agents Nebivolol Prasugrel Tecadenoson Moexipril Dalcetrapib Omapatrilat Otenzepad Vardenafil Ranolazine Arbutamine Hesperidin Landiolol Choline Fenofibrate Pratosartan Omecamtiv mecarbil Azimilide Darodipine Lemildipine Palonidipine Pentisomide Fenoldopam Oxodipine Eprosartan Finerenone More >>
Blood Glucose Regulators Gemigliptin Ponalrestat Balaglitazone Tofogliflozin Luseogliflozin Ruboxistaurin Nateglinide Bexagliflozin Dapagliflozin Zenarestat Ranirestat Vildagliptin Sorbinil MK-767 Melogliptin Fasiglifam Anagliptin AMG-131 Free Miglitol Empagliflozin Rivoglitazone Lacosamide Evogliptin Saroglitazar More >>
Anticonvulsants Losigamone Naluzotan JNJ-10234094 Remacemide Brivaracetam Pregabalin Rufinamide Eslicarbazepine Acetate Tiagabine Levetiracetam Perampanel Gabapentin Enacarbil Retigabine/Ezogabine
Blood Products Neu-2000 Fostamatinib Idrabiotaparinux Ataciguat Selfotel Azacitidine Avatrombopag Flindokalner Triflusal Apixaban Lubeluzole Momelotinib Orbofiban Rivaroxaban Dabigatran Etexilate Anagrelide Lefradafiban Avoralstat Ticagrelor CCX-168 Edoxaban Velifapon Rivipansel Danegaptide More >>

Antibacterials Cefilavancin Oritavancin Ritipenem acoxil Besifloxacin Ceftaroline Fosamil Levonadifloxacin Morinidazole Ceftizoxime alapivoxil Retapamulin LFF 571 Cethromycin Zabofloxacin Radezolid Plazomicin Surotomycin Pirfloxacin XF-73 Free Tebipenem Pivoxil Gemifloxacin Sitafloxacin Linezolid Brilacidin Zoliflodacin Alatrofloxacin More >>
Ophthalmic Agents Diquafosol Icoduline Nepafenac Omidenepag Isopropyl Alcaftadine Netarsudil NS-2 Latanoprostene bunod Levobetaxolol Ripasudil Travoprost Latanoprost Brinzolamide Bimatoprost Lifitegrast Emixustat
Gastrointestinal Agents Zamifenacin Dalcotidine Zaldaride Dexloxiglumide Racecadotril Renzapride Naloxegol Alvimopan Cilansetron Ibandronic Acid Lubiprostone Ibandronate Bevenopran Emoxipine Ulimorelin Prucalopride Revaprazan Velusetrag TD-8954 Esomeprazole Acotiamide Rabeprazole Eluxadoline Tenatoprazole More >>
Antidepressants Duloxetine 4-Chlorokynurenine Fengabine Befloxatone Quetiapine Aripiprazole Esketamine MK-0657 Wf-516 Amibegron Basimglurant Amitifadine Befuraline Fluparoxan Allopregnanolone Agomelatine Rapastinel Gepirone Escitalopram Levomilnacipran Desvenlafaxine Vortioxetine Vilazodone Sunipetron
Sleep Disorder Agents Almorexant R-228060 Armodafinil Adipiplon Lemborexant Tasimelteon Suvorexant Ramelteon Eplivanserin JNJ-42847922 Indiplon Pitolisant Zaleplon
Electrolytes Carglumic Acid Tolvaptan Deferasirox
Antigout Agents Arhalofenate Febuxostat Topiroxostat
Genitourinary Agents Prasterone Ulipristal Acetate Solifenacin Vibegron Imidafenacin Inaperisone Alfuzosin Flibanserin Tadalafil Sildenafil Solabegron Ospemifene Tolterodine Fesoterodine Dutasteride Mirabegron Antofloxacin Dapoxetine Darifenacin
Antiparasitics Fexinidazole AQ-13 Tafenoquine Phenothrin Artemisone Nitazoxanide Artefenomel
Metabolic Bone Disease Etelcalcetide Maxacalcitol Doxercalciferol Risedronic Acid

Antidementia Agents SB 742457 NTC-942 Ensaculin Idalopirdine VX 745 Semagacestat Lanabecestat Davunetide Donepezil Verubecestat Azeliragon T-807
Antipsychotics Encenicline BMY-14802-1 Lurasidone Ampalex Erteberel BL-1020 Neboglamine Risperidone Blonanserin Bitopertin ITI-007 Brexpiprazole Aripiprazole Lauroxil Raclopride Perospirone Olanzapine Paliperidone Pimavanserin Iloperidone Ziprasidone Cariprazine Asenapine
Antiparkinson Agents Lazabemide Istradefylline Etilevodopa Dipraglurant Sarizotan Tozadenant Ropinirole Rotigotine Rasagiline Safinamide Tolcapone Entacapone Opicapone Pramipexole Rivastigmine
Anxiolytics Saredutant Bretazenil Enciprazine Zatosetron Osemozotan Glemanserin
Dermatological Agents Pefcalcitol Orvepitant Asimadoline Ozenoxacin UR-1505 PAC 14028 Omiganan Bepotastine Crisaborole TU-2100 Tazarotene Tradipitant Benvitimod
Anti-inflammatory Agents Mesalazine Zidometacin Licofelone Flobufen Lumiracoxib Meloxicam Polmacoxib Esflurbiprofen ATB-346 Naproxcinod Etoricoxib Rofecoxib Grapiprant GW-406381 Dilmapimod Celecoxib Balsalazide Imrecoxib Filgotinib
Analgesics Debio-0827 Spiradoline Pregnanolone Zucapsaicin Bicifadine Tapentadol Benzhydrocodone Parecoxib
Genetic/Enzyme Disorder Obeticholic Acid Miglustat Glycerol phenylbutyrate Eliglustat
Antimigraine Agents Dotarizine Ubrogepant Lasmiditan Rizatriptan Telcagepant Eletriptan Frovatriptan
CNS Agents Dalfampridine ALKS-8700 Teriflunomide Ponesimod Laquinimod Atomoxetine Dexmethylphenidate Edivoxetine Fingolimod Gaboxadol Arimoclomol

Antiemetics Dolasetron Aprepitant Palonosetron Fosaprepitant Rolapitant
Anti-Addiction Agents Kakonein Varenicline
Anesthetics Remimazolam besylate Ropivacaine Fospropofol Levobupivacaine Remimazolam
Antispasticity Agents Arbaclofen
Skeletal Muscle Relaxants Cisatracurium Besylate

Inhibitors/Agonists

PI3K/Akt/mTOR Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN RSK PI3K Autophagy SRPK
Biochemical Reagent Intermediate and Others
Neuronal Signaling Dopamine Receptor Adrenergic Receptor 5-HT Receptor AChE NK Receptor Substance P SSRIs CaMK DAT mGluR Amyloid-β MT Receptor CGRP Receptor Imidazoline Receptor AChR AMPAR GABA Receptor NMDAR Opioid Receptor Cannabinoid Receptor OXTR
Stem Cells/Wnt Hedgehog PKA Smo TGF-beta/Smad PORCN Notch Gli sFRP-1 mTOR PKC Oct ROCK MST
Ubiquitin E1/E2/E3 Enzyme p97 DUB Proteasome NAE
Protein Tyrosine Kinase/RTK PDGFR Trk Receptor c-Kit VEGFR HER2 Src FGFR ALK c-Met/HGFR Syk c-FMS Tie-2 TAM Receptor IGF-1R BTK Insulin Receptor Ros1 ITK Ack1 Ephrin Receptor BMX Kinase DDR1/DDR2 Receptor DYRK
TGF-beta/Smad ROCK TGF-beta/Smad PKC
ADCs ADC Linker ADC Linker with Payload
Anti-infection Antibacterial Antifungal Antiparasitic CMV Filovirus HBV HCV HIV HIV Integrase HIV Protease HRV HSV Influenza Virus NNRTI NRTI Orthopoxvirus Reverse Transcriptase RSV SARS-CoV CCR
Apoptosis Apoptosis Inducer Bcl-2 Caspase c-Myc c-RET DAPK IAP MDM2 p53 PD-1/PD-L1 PERK PKD Survivin Thymidylate Synthase TNF-alpha RIP Kinase FAS G-quadruplex

Autophagy Autophagy CXCR LRRK2 SPHK ULK MLK
Immunology/Inflammation CCR Complement System COX CRTH2 CXCR FLAP Histamine Receptor IFNAR IL Receptor IRAK LTR MALT1 MyD88 NADPH Oxidase NLR NOS Nrf2 PD-1/PD-L1 PGE Synthase ROS SIK STING Thrombopoietin Receptor TLR More >>
Biochemical Reagents Biochemical Assay Reagent Dye Reagent Intermidate and Others
Cell Cycle APC Aurora Kinase Casein Kinase CDK Chk c-Myc CRM1 DHFR DNA/RNA Synthesis FOX G-quadruplex Haspin Kinase LIMK Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog PAK PD-1/PD-L1 PERK PLK PPAR PTEN RAD51 Rho More >>
Cytoskeleton Akt Arp2/3 Complex Bcr-Abl Dynamin FAK Gap Junction Protein HSP Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK PKC Wnt β-catenin
DNA Damage ATM/ATR DNA/RNA Synthesis DNA Alkylator/Crosslinker DNA-PK HDAC MTH1 PARP Sirtuin Telomerase Topoisomerase RAD51
Endocrinology/Hormones 5 Alpha Reductase ACE Androgen Receptor Aromatase ERR Glucocorticoid Receptor GPCR Opioid Receptor Progesterone Receptor Renin Neprilysin GNRH Receptor OXTR Angiotensin Receptor Adiponectin Receptor GHSR Neuropeptide Y receptor TSH Receptor
Epigenetics Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP Pim Sirtuin
GPCR/G Protein Cannabinoid Receptor OXTR LPL Receptor Angiotensin Receptor Vasopressin Receptor Ras cAMP Endothelin Receptor GNRH Receptor Prostaglandin Receptor Bradykinin Receptor Glucagon Receptor CaSR SSTR P2Y Receptor Guanylate Cyclase Motilin Receptor LPA Receptor PAFR RGS PAR Urotensin Receptor Neuropeptide Y receptor GHSR More >>
JAK/STAT Signaling EGFR JAK Pim STAT FLT3

MAPK/ERK Pathway ERK JNK MEK MLK MNK p38 MAPK Raf RSK ZAK
Membrane Transporter/Ion Channel AChR AMPAR ATPase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel EAAT2 GABA Receptor GlyT1 HCN Channel MAT MCT Na+/Ca2+ Exchanger Na+/K+ ATPase NBC NKCC NMDAR Oct P2X Receptor P-gp Potassium Channel Proton Pump More >>
Metabolic Enzyme 15-PGDH 5 Alpha Reductase ACC ACE Adenosine Deaminase Adenosine Kinase AhR ALDH Aldose Reductase Aminopeptidase ATP Citrate Lyase Carbonic Anhydrase Cathepsin CETP COMT CPA Decarboxylase Dehydrogenase DGAT DHFR Elastase Enolase FAAH FABP More >>
Natural Products Alkaloids Cerebrosides Chalcones Coumarins Diterpenoids Flavonoids Iridoids Lignans Lipids Miscellaneous Monoterpenoids Naphthols Other Terpenoids Phenols Phenylpropanoids Quinones Saccharides Sesquiterpenoids Tetraterpenoids Thiophenes Triterpenoids Xanthones Nature Product Other Natural Product
NF-κB NF-κB RIP Kinase IKK TAK1 NOD1
Other Inhibitors Other Targets Phosphatase VDA Others
Protease Caspase Cysteine Protease DPP4 Glutaminase HIV Protease MMP Proteasome Secretase Ser/Thr Protease Tyrosinase Cathepsin PAI-1

Materials Science

Nanomaterials Carbon Nanomaterials Dendrimers Gold Nanoparticles Iron Oxide Nanoparticles Ceramic Membranes Mesoporous Materials Nano Minerals: Nanoclays Materials by Application Metals&Metal Alloys Oxides&Nitrides Nanopowders & Nanoparticle Dispersions Nanowires Quantum Dots Silsesquioxanes Silver Nanoparticles Surface Functionalized Nanoparticles
Electronic Materials Battery Materials Molecular Conductors Perovskite Solar Cell (PSC) Materials Dye-Sensitized Solar Cell (DSSC) Materials Liquid Crystal (LC) Materials Organic Transistor (OFET) Materials Organic Solar Cell (OPV) Materials Self Assembly Materials Organic Light-Emitting Diode (OLED) Materials
Magnetic Materials Magnetic Metal Complexes Magnetic Ionic Liquids Organic Radicals Magnetic Material
Organic Pigments Organic Pigment
Optical Materials DCM Dyes Perylene Dyes Dipyrromethene Dyes Other Functional Dyes Photochromic Dyes Cyanine and Squarylium Dyes Near-Infrared (NIR) Dyes Visible Light Photoredox (VLP) Catalysts Quinacridone Dyes Heat and Pressure Sensitive Dyes Phthalocyanine and Porphyrin Dyes Coumarin Dyes Organic Non-Linear Optical (NLO) Materials Xanthene Dyes Fluorescence Materials Fluorescent Probes
Material Others Mateial Other
Polymer Science Monomers Polymerization Reagents Polymer Additives Polymers Resins
Material Building Blocks Supramolecular Host Materials Ligands for Functional Metal Complexes Polymer and Macromolecule Semiconductor Building Blocks Phthalocyanine Building Blocks Small Molecule Semiconductor Building Blocks Liquid Crystal (LC) Building Blocks Solubility Enhancing Reagents

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HomeInhibitors/AgonistsStem Cells/WntNotch

Notch Inhibitors

Notch(6 Products)

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Products (6):

FLI-06

CAS No.: 313967-18-9

98+%

LY3039478

CAS No.: 1421438-81-4

95+%

Semagacestat

CAS No.: 425386-60-3

98+%

BMS-983970

CAS No.: 1584713-87-0

98+%

IMR-1

CAS No.: 310456-65-6

97%

IMR-1A

CAS No.: 331862-41-0

97%

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